More Evidence of Reversibility

New research from Canada provides additional demonstration of reversibility of MECP2-related disorNews iconders. Researchers from the University of Toronto and the Hospital for Sick Children have demonstrated that the volume of specific areas the adult brains of Rett syndrome mice actually undergo a growth spurt withe the normalization of levels of MeCP2  protein. These results were presented in San Diego on November 16, 2016 at the Annual Meeting of the Society for Neurosciences.

These findings are consistent with previous research on reversibility, such as those from the Zoghbi lab at Baylor, and also provides additional new information on the normalization of brain volume.This growth spurt in adult brains is quite an exciting finding, even if some caution is required in generalizing this finding from lab mice to humans.

More information can be found here.

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