This compilation of home videos illustrates one individual with MECP2 Duplication Syndrome and his walking at various ages over a period of two decades. It indicates his progression and regression of skills. Of course, every individual with MECP2 Duplication Syndrome is different, many will never walk and some will begin walking younger, develop even more advanced skills, and maintain them longer. We are sad to see some of Dave’s skills slipping away but grateful for what he was able to achieve and what he still can do. I think Dave’s walking, however, is fairly typical for those who do develop walking.