MeCP2 and Cocaine Addiction

18 August 2010 – Jupiter, FL, USA Lab researchers at the Scripps research Institute have found a link between methyl CpG binding protein 2 (MeCP2), the protein produced by the MECP2 gene and cocaine addiction in lab rats. When MeCP2 levels were high, rats were more vulnerable to addiction and cocaine exposure also increased the level of the protein. At first glance this seems to have little direct relevance to those born with extra MECP2 gene copies, but this and a wide variety of other studies now probing the role of MECP2 may eventually help clarify how the gene operates and whether somethings may be useful in up-regulating or down-regulating the gene activity. For more, on this see: Epigenie

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One response to “MeCP2 and Cocaine Addiction

  1. Your reader might be interested in reading a blog post about the MECP2/drug addiction connection on the Rett Syndrome Research Trust blog,
    http://rettsyndrome.wordpress.com/2010/09/05/mecp2-beyond-rett/

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